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Pink reportedly wanted “U + Ur Hand” to be the second single from I’m Not Dead, but “Who Knew” was released as the second and “U + Ur Hand” was instead released as the third. The single had success in Europe, reaching number ten in the UK, number four in Germany and number 11 in France; it peaked inside the top ten on the European Hot 100 Singles chart.

Pink wrote the song with Max Martin, Luke Gottwald, and Rami to mock the men who would flirt with her in clubs. The title refers to the line “looks like it’s just me and my hand tonight,” which was a phrase she’d heard guys using.